large study confirms effectiveness of Pfizer vaccine

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A large study of more than 1.2 million people in Israel shows that Pfizer’s vaccine is 94% effective against symptomatic cases of Covid-19. This is excellent news which confirms the excellent results of the vaccine in clinical trials.

According to a study published this Wednesday in the journal New England Journal of Medicine, the vaccine jointly developed by Pfizer (United States) and BioNTech (Germany) is 94% effective against symptomatic cases of Covid-19. These very encouraging results are consistent with the announcement made by the two structures last November, suggesting that their vaccine was 95% effective in preventing infections, building on the preliminary results of their large-scale phase 3 trial.

The fact that vaccines have worked so well in the real world … really suggests that if the nations of the world can find the will, we now have the means to end COVID-19 forever.“Said Ben Neuman, a virologist at Texas A&M University who was not involved in the research.

Credit: Fotoarena / Sipa USA / SIPA

1.2 million people affected

As part of this experiment, carried out in Israel in the Clalit Health Services between December 20, 2020 and February 1, 2021, approximately 1.2 million people were divided into equal groups of vaccinated and unvaccinated. Each vaccinated subject was matched to an unvaccinated “control” person with similar characteristics in terms of sex, age, but also comorbidities and place of residence.

By comparing the data of the two groups, the researchers then underlined an effectiveness against the symptomatic infections of 57% between 14 and 20 days after the first dose, then to 94% seven days after the second dose. Note that the effectiveness of the vaccine was relatively constant for all age groups with slightly lower results for people with co-morbidities.

These results are all the more impressive given that the English variant was already circulating in Israel at that time, according to the authors. The country, where 4.25 million inhabitants have already received their first dose, aims to vaccinate the entire population over the age of sixteen by the end of March.

In France, remember that general practitioners and those at work can administer the AstraZeneca / Oxford vaccine to people aged 50 to 64 with comorbidities since Thursday, February 25.

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